Relationship Between Prostate Cancer and Atypical Small Acinar Proliferation (Part-2)

Relationship Between Prostate Cancer and Atypical Small Acinar Proliferation (Part-2)


In our center, prostatic adenocarcinoma was detected in 34% of the follow-up biopsies of ASAP-diagnosed cases in the first biopsies. In 38% of cases, cancer localization and ASAP are in different parts. Consistently with the literature, this situation shows that recurrent biopsies in ASAP cases and biopsies performed from different localizations are significant in catching malign cases. It is urgent to prostate cancer to treat prostate to cancer. Start taking drugs for prostate treatment can be in a Canadian pharmacy online. Canadian medicine is very famous all over the world.

prostate cancer


No acknowledgement to declare.


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Figure Legends

Figure 1a-1b:  Atypical small acinar proliferation, suspicious for cancer. A cluster of acini with atrophy and architectural distortion. Despite architectural distortion, nuclear features are not enough for diagnosis of cancer (figüre 1a: hematoxylin-eosin, original magnification x 200)- (figüre 1b: hematoxylin-eosin, original magnification x 400).

Figure 2a-b: Adenocarcinoma focus in the follow-up biopsy that diagnosed as ASAP in the first biopsy (figüre 2a: hematoxylin-eosin, original magnification x 200)- (figüre 2b hematoxylin-eosin, original magnification x 400).


Table: Location of atypical small acinar proliferation in the first biopsy and cancer in follow-up biopsy
Patients No ASAP site Cancer site Patients No ASAP site Cancer site
1 1 6,7,8,9,10 12 2 5,9,11
2 5 9,11 13 4 10,13
3 5 5,7,8 14 4 4,9,11
4 7,9 1,3,6,7,8,9,10 15 3 11
5 1 5,6 16 6 1,2
6 8 4,5,8 17 11 2,3,11
7 3,9,11,12 1,3,11 18 7,10 1,7,8,10
8 5,10,11 10,11 19 4,6,7,9 7,9
9 2 9 20 2 1,2
10 3 1,3 21 12 1,3,12
11 9 1,6,9
1: Right Base, 2: Right Lateral Base, 3: Right Medial, 4: Right Median-Lateral, 5: Right Apex, 6: Right Lateral Apex, 7: Left Base, 8: Left Lateral Base, 9: Left Medial, 10: Left Median-Lateral, 11: Left Apex, 12: Left Lateral Apex

By Dr. Ravi Mootha, M.D. On: May 07, 2019 at 19:43:19